Project leader

Professor Swaran Singh (MBBS MD FRCPsych DM)

Head of Division, Mental Health and Wellbeing
Honorary Consultant Psychiatrist
Hub Lead, Mental Health Research Network (MHRN)
Commissioner, Equality and Human Rights Commission

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Project staff

Dr Helena Tuomainen

MILESTONE Scientific Manager 

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Prof. Dieter Wolke

Professor, Department of Psychology

Dr Jason Madan

Assistant Professor

Dr Jane Warwick

Professor of Clinical Trials

Dr Moli Paul

Principal Clinical Teaching Fellow

Priya Tah

Research Assistant

Rose-Marie Lomax

Project administration

Rebecca Appleton

Research Assistant 

Institute presentation

The University of Warwick is globally connected, forward-looking and entrepreneurial. We create new ways of thinking and achieving: making us stand out from our competitors and the more ‘traditional universities’ and creating an inspiring place to study and undertake research.

Warwick is one of the UK’s great success stories. In less than fifty years since being founded we’ve become one of the UK’s best universities, consistently at the top of UK league tables and we’re rapidly climbing the international league tables of world class universities.

The Division of Mental Health and Wellbeing focuses on applied research into development and transitions across the life span, early interventions, prevention of illness and promotion of wellbeing.

We are a unique combination of experts in psychiatry, public health, cardiovascular health, psychology, social sciences and community paediatrics, interested in a life course approach. Our research activities include epidemiology, trials of complex interventions at individual, family and community levels, and understanding socio-cultural and environmental determinants of mental health and wellbeing. Our academic teams staff are internationally renowned for their impact on improving mental health and wellbeing across the life span, and in both clinical groups and the general population.

Warwick Medical School project staff works on Work Packages 3, 4 and 5:

Work package 3 objectives

This work package will deliver a prospective cohort study of CAMHS (Children and Adolescent Mental Health Services) users whose care will finish because they have reached transition age for their CAMHS. This cohort will include service users for both the experimental and control clusters (WP4). We will use a longitudinal observation study design that repeatedly assesses the mental health and functioning from late adolescence into early adulthood. It will identify those who would benefit most from long-term care and transition into AMHS (Adult Mental Health Services) care and those who show no deterioration or improvements in mental health without further AMHS care. Because of the variation in services offered, different ages at transition from child/adolescent to adult services, and differences in types of care across European countries, we will include eight countries in this prospective, multisite cohort study of adolescents who reach the specific age of transition within each participating service.

Relevant national ethics committee and research governance approvals will be in place in all partner study centres (following the work undertaken in WP6) before recruitment of young people for both the experimental and control clusters commences. The MILESTONE SOP (Standard Operating Procedures) will underpin data collection processes at all study time points.

Work package 4 objectives

The overall aim of this WP is to determine the effectiveness of an innovative model of managed transition (including appropriate discharge from CAMHS care) in improving the outcomes of young people who reach the transition boundary between CAMHS and AMHS. In WP2 we will have developed a Transition Readiness Measure (TRaM) that identifies high-risk, high-need cases for whom transition to AMHS is critical and also those who can be appropriately discharged from CAMHS. WP2 will also develop Transition Outcome Measures (TrOM) for assessing the quality and outcomes of transitional care. In WP3 we will recruit a cohort of about 1000 service users who reach the transition boundary in the participating services, from which we will identify CAMHS services and users for participation in the cluster randomised trial of WP4.

Work package 5 objectives

The overall aim of this work programme is to evaluate the cost-effectiveness of a managed transition model by assessing its resource use implications and long-term health impact. Analyses will be structured around a decision model informed by a number of sources, including the randomised controlled trial of the TRaM intervention and a systematic review of the relevant literature.

Estimate the cost-effectiveness of TRaM, and explore the sensitivity of cost-effectiveness to different systemic contexts.